I have C677T homozygote MTHFR deficiency and I’m currently 5 weeks pregnant. I’ve been taking Solgar Folate (as metafolin) 800 mcg 3x/day plus New Chapter Perfect Prenatal Multi-vitamin (which contains 600mcg of folate (as folic acid) in a daily dose.
She was tested due to behavior problems (ADHD, ODD and bipolar with psychosis). Her pediatrician believes she is not bipolar but that her manic/bipolar symptoms may be from folate deficiency. Dr Jill, I’m confused. I thought methyl folate (as opposed to synthetic folic acid) was crucial for patients with MTHFR to take and have started taking it myself. I understand you cannot give medical advise through your blog but please consider my situation.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. I believe that everyone needs to find a practitioner that will let him/her be a part of the healthcare team.
How to Naturally Treat MTHFR Gene Mutation
After coming across an article on anxiety and depression and its possible link to MTHFR mutation, I decided to order this gene test as I have had chronic anxiety for the past 12 years and intermittent periods of depression. I am 34 years old and apart from living with an extremely disruptive form of social anxiety which responded to none of the many treatments I tried for it, I am otherwise physically healthy and try to eat well and exercise regularly. I suggest you consult with your doctor or find a functional medicine physician trained with MTFHR mutations in your area. So,pls tell me what to do to avoid bad effects of MTHFR mutation. Hi Kelly, one mutation commonly causes a decrease in activity of that particular gene so it does play into health and disease.
And guess what? Acid-suppressing medications made the symptoms worse and did nothing to remove the underlying root cause (in my case, my food sensitivity to dairy). Even more important, my research pointed out that the issue for people having Hashimoto’s wasn’t their having too much acid! The reality is that most people with Hashimoto’s have too little or even no stomach acid.
It just doesn’t allow us to spend enough time with the patient. Great article, thank you Dr. Jill. This is a bit easier for me to take in than Dr. Lynch’s protocol.
For non-prescription products, read the label or package ingredients carefully. Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects . The use of too much acetaminophen and salicylates at the same time may cause kidney damage or cancer of the kidney or urinary bladder.
- My doctor has had me start taking 5-mthfr and alpha lipoid acid.
- My test results were positive for one copy of the C677T mutation and one copy of the A1298C mutation, or compound heterozygous for the mutations.
- So who would be best, endocrinologist, Neurologist, or?
- I have recently found out that I am heterozygous c677t.
The following side effects may mean that a serious allergic reaction is occurring. Check with your doctor or get emergency help immediately if they occur, especially if several of them occur at the same time. Do not take this medicine for 5 days before any planned surgery, including dental surgery, unless otherwise directed by your medical doctor or dentist.
I did the 23andme testing as well as Genomind testing with a doctor some time ago and was able to determine that I had an MTHFR mutation. It’s also important to note that MTHFR gene mutation is a complex and very individualized condition.
inactivated form of folate (one of the B vitamins). In order to be converted into an active usable form by the body, it must undergo methylation. Ingesting high levels of folic acid can be toxic for those with MTHFR gene mutation. It is important to keep in mind that not all doctors are well-versed in MTHFR issues. For this reason, it may be a good idea to seek out a functional medicine practitioner or another healthcare professional that has experience treating patients with MTHFR gene mutations.
I believe I have other mutations than just the Hetero for C677T but I didn’t get our genetic testing ordered before the FDA shut down the 23andMe results from being released so I need to look into other ways to get this information. I attempted the methylfolate/B12 protocol and even at an extremely low dose I had extreme side effects and reaction so I know something else is at play. I’m pregnant now and need to explore my other options for getting the supplementation I need!
Considerations Relating to PPIs and Other Acid Blockers
I have the Mthfr mutation that promotes poor histamine health, but I think I have a fungal/mold issue as well, because while I was on turbinifine for three months I had almost no angioedema episodes. MTHFR gene mutations do contribute to histamine issues in many people… but other things like mold/mycotoxin exposures destabilize mast cells and create histamine issues as well. Hello Dr. Carnahan, I am so glad that I have found your website as I have been dealing with recurring idiopathic angioedema episodes for the last six years. I have tested positive for the mthfr gene with the t/t combination. I have been to numerous allergy specialists, including top academics in the field and no one has suggested that this gene mutation could explain the cause of the angioedema.
I dont think the Bio K+ had anything to do with the situation. Although some people have funny reactions to some probiotics. The problem was most likely caused by years of inappropriate diet (although I have no idea what you eat) as it is with most people. The Bio K+ may have just highlighted it.